Contains EpiCorﾨ, which is clinically proven to reduce the incidence of cold and flu symptoms
Helps to maintain immune function
Includes European elderberry extract and vitamin C for additional relief of cold and flu symptoms Cor Defence contains EpiCorﾨ, a proprietary nutrient extract from Saccharomyces cerevisiae yeast that is clinically proven to reduce the incidence of cold and flu symptoms. Cor Defence also includes zinc to help maintain immune function, as well as European elderberry flower extract and vitamin C, which help to relieve cold symptoms and provide a source of antioxidants. The proprietary fermentation process used in the production of EpiCor stresses yeast cells to increase the concentration of bioactive components, including yeast glucans (beta-1-3-glucan and beta-1-6 glucan), polyphenols and vitamins and minerals1. In vitro EpiCor studies have demonstrated anti-inflammatory effects, such as the stimulation of B lymphocytes and natural killer cells.2 In a randomised, double-blind, placebo-controlled clinical trial of 116 healthy participants not vaccinated with the influenza vaccine, daily supplementation EpiCor significantly reduced both the incidence and duration of cold and flu-like symptoms. Elderflower and its extracts have a history of traditional use for the relief of early symptoms of common cold.4 Zinc helps to maintain immune function.5 Vitamin C may help to prevent and relieve cold and _u symptoms. A controlled study evaluated the effects of a megadose of vitamin C in the prevention and relief cold and flu symptoms in 252 test and 463 control participants. Participants in the control group that experienced cold or flu symptoms were treated with conventional medications (pain relievers and decongestants), while participants in the treatment group were treated with hourly 1000 mg doses of vitamin C for the first 6 hours and then 3 times daily afterwards. The treatment group experienced an 85% decrease in overall reported flu and cold symptoms after vitamin C supplementation.6 04275 NPN 80049459 REFERENCES 1. Jensen G, Carter S, Reeves S, Robinson L, and Benson K. Anti-In_ammatory Properties of a Dried Fermentate In Vitro and In Vivo. Journal of Medicinal Food. 2014; 00(0): 1-7 2. Jensen G, Hart N, and Schauss G. An anti-inflammatory immunogen from yeast culture induces activation and alters chemokine receptor expression on human natural killer cells and B lymphocytes in vitro. Nutrition Research. 2007; 27: 327-335 3. Moyad MA, Robinson LE, Zawada ET Jr, Kittelsrud JM, Chen DG, Reeves SG, Weaver SE. Effects of a modified yeast supplement on cold;_u symptoms. Urol Nurs. 2008 Feb;28(1):50-5. 4. Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Riggins C, Rister R. The Complete German Commission E Monographs – Therapeutic Guide to Herbal Medicines. American Botanical Council and Integrative Medicine Communications. Boston, MA: USA; 1998. 5. NHPD Monograph on Zinc (from non-picolinate sources). 2014-03-24 6. Gorton HC, Jarvis K. The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections. J Manipulative Physiol Ther. 1999 Oct;22(8):530-3.